Drug immunogenicity may generate significant hypersensitivity reactions that may progress to the development of auto-antibodies to the patient's natural version of that protein.
Use our well-characterized immunospecific reagents to:
Investigate baseline or pretherapy immune response
Detect post-therapy titer increases
Screen for neutralizing antibodies
Correlate antibody titer to response to therapy
Map epitopes of the immunogenic portion of a drug
Distinguish between immunogenicity of a therapeutic drug and the natural form of the protein
Distinguish between immune response to a drug and process contaminants, such as host cell proteins
Isotype and subtype antibodies involved in the immunogenic response
Human IgG screening kits for sensitive, specific, and reproducible monitoring to investigate immune response to protein therapeutics or contaminant bioprocess impurities.