Immunogenicity Analysis

Drug immunogenicity may generate significant hypersensitivity reactions that may progress to the development of auto-antibodies to the patient's natural version of that protein.

Use our well-characterized immunospecific reagents to:

  • Investigate baseline or pretherapy immune response
  • Detect post-therapy titer increases
  • Screen for neutralizing antibodies
  • Correlate antibody titer to response to therapy
  • Map epitopes of the immunogenic portion of a drug
  • Distinguish between immunogenicity of a therapeutic drug and the natural form of the protein
  • Distinguish between immune response to a drug and process contaminants, such as host cell proteins
  • Isotype and subtype antibodies involved in the immunogenic response
 
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