The host cells used for recombinant expression contain hundreds to thousands of host cell proteins (HCPs) that can contaminate biopharmaceutical products. Failure to sufficiently reduce impurities early in drug development can reduce drug efficacy or lead to adverse patient reactions. Regulations require reduction of HCPs to the lowest levels possible.
Use our generic kits for host cell protein analysis:
ELISA kits for the detection of <1 ppm host cell proteins from a variety of cell lines commonly used in the production of complex therapeutic proteins.
ELISA kits for the detection of <1 ppm of host cell proteins from P. pastoris and S. cerevisiae.
Generic and custom kits for the detection of contaminating proteins from a range of host species.
ELISA kits for the detection of <1 ppm host cell proteins from E. coli, L. lactis, P. fluorescens, and S. aureus.