Antibody Affinity Extraction Outperforms Native Digestion as a Sample Preparation Method for LC-MS Detection of Host Cell Proteins in Drug Substances
HCP detection and quantitation: a review of ELISA, MS and Antibody Affinity Extraction immunoaffinity chromatography (Bioanalysis Zone - Tech Digest)
KC Gulla, et al. High throughput chromatography and analytics can inform viral clearance capabilities during downstream process development for biologics. Biotech Journal. 2021
Viral Clearance in a Downstream AAV Process - Case Study Using a Model Virus Panel and a Noninfectious Surrogate
Dyer R, Song Y, Chen J, et al. Mechanistic insights into viral clearance during the chromatography steps in antibody processes by using virus surrogates. Biotechnol Progress. 2020;36:e3057.
