The manufacture of products by various biotechnological processes such as cell or tissue culture can result in residual contamination of the desired product by components used in the culture media.
The use of so called serum free defined media greatly reduces the number of potential contaminants but it may still be necessary to determine trace contamination levels of the proteins and growth factors used in these media. When the intended product is used as a therapeutic agent in humans or animals the product should be highly purified to avoid potential health risks or other problems that might result from trace contaminants.
Efforts to reduce trace media contamination to the lowest levels practical through optimal process design, validation, and final product testing require a sensitive and reliable analytical method. Cygnus offers highly sensitive ELISA kits for the detection of specific bioprocess contaminants.